An Interactive Annotated World Bibliography of Printed and Digital Works in the History of Medicine and the Life Sciences from Circa 2000 BCE to 2024 by Fielding H. Garrison (1870-1935), Leslie T. Morton (1907-2004), and Jeremy M. Norman (1945- ) Traditionally Known as “Garrison-Morton”

16061 entries, 14144 authors and 1947 subjects. Updated: December 10, 2024

Permanent Link for Entry #15746

  • 13472

Defining criteria for autoimmune diseases (Witebsky's postulates revisited).

Immunol. Today, 14, 436-30, 1993.

In 1993 Rose and Bona revised Witebsky's postulates "based on direct evidence from transfer of pathogenic antibody or pathogenic T-cells, indirect evidence based on reproduction of the autoimmune disease in experimental animals and circumstantial evidence from clinical clues.:[5]

  • Auto-antibodies detectable in all cases of disease.
  • Experimentally reproducible by immunization with antigen.
  • Experimental disease must show immunopathological lesions that parallel those in the natural disease.
  • Transferable by serum or lymphoid cells." (Wikipedia article on Ernst Witebsky, accessed 8-2021).


Subjects: IMMUNOLOGY
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