An Interactive Annotated World Bibliography of Printed and Digital Works in the History of Medicine and the Life Sciences from Circa 2000 BCE to 2024 by Fielding H. Garrison (1870-1935), Leslie T. Morton (1907-2004), and Jeremy M. Norman (1945- ) Traditionally Known as “Garrison-Morton”
Permanent Link for Entry #16627
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Conservation of the sequence and temporal expression of let-7 heterochronic regulatory RNA.Nature, 408, 86-89, 2000.Working with the let-7 gene, the authors led by Ruvkun showed that microRNA encoded by the let-7 gene was highly conserved, and present throughout the animal kingdom, proving that gene regulation by microRNA is universal among unicellular organisms on Earth. This paper, published seven years after the initial discovery (No. 14301) provided the evidence to convince skeptics of the existence of microRNA. Subjects: BIOLOGY › MOLECULAR BIOLOGY › Molecular Biology Permalink: historyofmedicineandbiology.com/id/16627 |