An Interactive Annotated World Bibliography of Printed and Digital Works in the History of Medicine and the Life Sciences from Circa 2000 BCE to 2024 by Fielding H. Garrison (1870-1935), Leslie T. Morton (1907-2004), and Jeremy M. Norman (1945- ) Traditionally Known as “Garrison-Morton”

16076 entries, 14164 authors and 1948 subjects. Updated: January 31, 2025

Permanent Link for Entry #16658

  • 14333

Crystal structure and mechanism of a calcium gated potassium channel.

Nature, 417, 515-522, 2002.

The authors first obtained the crystal structure of a Ca2+ - gated K+ ion channel and then deciphered how ion channels open and close, a process called "gating" in response to cues in their environment. They determined the structure of the opened state and revealed the complex molecular nature of the way gating transitions occur.
In 2003 Roderick MacKinnon shared the Nobel Prize in Chemistry Peter Agre with  “for discoveries concerning channels in cell membranes."

Order of authorship in the original publication: Jiang, Lee, Chen...MacKinnon.

(Thanks for Juan Weiss for this reference and its interpretation.)



Subjects: NOBEL PRIZES › Nobel Prize in Chemistry (selected)
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