Cooper, the pupil and great interpreter of Hunter, was the most popular surgeon in London during the Regency. In 1802 he gained the Copley Medal of the Royal Society. Travers was surgeon to St. Thomas’s Hospital, and particularly distinguished himself in vascular surgery and ophthalmology. The book includes a description of “Cooper’s tumor”.

In 1817 Cooper ligated the abdominal aorta. The patient died next day, but examination showed that his aorta was so diseased that he could never have recovered, while the ligation was so well performed that with a lesser degree of aortic disease the man would probably have survived. Cooper published the report of this operation in Vol. 1, 101-30.