Seminal work on renal tumors with unsurpassed descriptions of the clinical semiology of these diseases. In 1903 Albarran was the first "... to diagnose transitional cell carcinoma of the renal pelvis by detecting malignant cells in urine aspirated from the renal pelvis. He further refined this approach by noting ureteral hemorrhage in the presence of a renal pelvic cancer when fluid injected in the renal pelvis distended it and caused it to bleed (Albarran’s sign)” (Wein AJ et al.: Campbell-Walsh Urology,1413). Digital facsimile from the HathiTrust at this link.