An Interactive Annotated World Bibliography of Printed and Digital Works in the History of Medicine and the Life Sciences from Circa 2000 BCE to 2024 by Fielding H. Garrison (1870-1935), Leslie T. Morton (1907-2004), and Jeremy M. Norman (1945- ) Traditionally Known as “Garrison-Morton”

16061 entries, 14144 authors and 1947 subjects. Updated: December 10, 2024

BERG, Paul

2 entries
  • 257.3

Biochemical method for inserting new genetic information into DNA of simian virus 40: Circular SV40 DNA molecules containing Lambda phage genes and the galactose operon of Escherichia coli.

Proc. Nat. Acad. Sci. (U.S.A.), 69, 2904-2909, 1972.

First recombinant DNA molecules generated. Digital facsimile from PubMedCentral at this link.

In 1980 Berg was awarded half of the Nobel Prize in Chemistry "for his fundamental studies of the biochemistry of nucleic acids, with particular regard to recombinant-DNA." The other half was awarded  to Walter Gilbert and Frederick Sanger "for their contributions concerning the determination of base sequences in nucleic acids."



Subjects: BIOLOGY › MOLECULAR BIOLOGY › Recombinant DNA, NOBEL PRIZES › Nobel Prize in Chemistry (selected)
  • 12304

Expression of a bacterial gene in mammalian cells.

Science, 209, 1422-1427, 1980.

(Order of authorship in the original publication: Mulligan, Berg.) In an understated paper the authors suggested the potential of treating recessive diseases like Lesch-Nyhan syndrome by gene therapy.

(Thanks to Juan Weiss for this reference and its interpretation.)



Subjects: BIOLOGY › MOLECULAR BIOLOGY, GENETICS / HEREDITY › GENETIC DISORDERS, GENETICS / HEREDITY › Gene Therapy / Human Gene Transfer