An Interactive Annotated World Bibliography of Printed and Digital Works in the History of Medicine and the Life Sciences from Circa 2000 BCE to 2022 by Fielding H. Garrison (1870-1935), Leslie T. Morton (1907-2004), and Jeremy M. Norman (1945- ) Traditionally Known as “Garrison-Morton”

15961 entries, 13944 authors and 1935 subjects. Updated: March 22, 2024

ROWLAND, Raymond R. R.

1 entries
  • 11848

Gene-edited pigs are protected from porcine reproductive and respiratory syndrome virus.

Nature Biotechnology, 34, 20-22, 2015.

Order of authorship in the original publication: Whitworth, Rowland, Ewen, ... Prather. Using the CRISPR Cas molecular gene-editing tool, Prather and colleagues edited the gene that codes for the CD163 protein in adult male and female pigs gametes (sperm and egg) that acts similar to a receptor to which the Porcine reproductive and respiratory syndrome virus (PRRSV) attaches. This artificial genetic mutation created offsprint piglets that were resistant and immune to this panzootic infection which was previously lethal and incurable.

(Thanks to Juan Weiss for this reference and its interpretation.)



Subjects: BIOLOGY › MOLECULAR BIOLOGY › CRISPR , BIOLOGY › MOLECULAR BIOLOGY › CRISPR Gene Editing, IMMUNOLOGY, VETERINARY MEDICINE, VETERINARY MEDICINE › Panzootics, VIROLOGY, WOMEN, Publications by › Years 2000 -