Invention of the modern sphygmograph. Also published in C.R. Acad. Sci. (Paris), 1860, 51, 281-309. Preliminary paper in same journal, 1860, 50, 634-37.

Marey’s law of the heart. Marey was the first to realize the relationship between the blood pressure and the heart rate.

First direct records of the heart impulse by means of a “cardiac sound” and the sphygmograph – recording tambours, which wrote on a moving drum covered with smoked paper.

Marey first recorded atrial fibrillation in this work work in which he used pulse tracings to establish the interelationship of heart rate and blood pressure. The work also includes the first detailed description of the technique of cardiac catheterization that Marey developed with Jean Baptiste Chauveau. "With Chauveau he was the first to perform cardiac catheterization on living horses" (Bedford 260). Digital facsimile from BnFGallica at this link.

Marey pioneered the use of graphical recording in the experimental sciences, using instruments (many of his own invention) to capture and display data impossible to observe with the senses alone, and to record the progression of such data over time. He began by applying graphical recording methods to problems in physiology, using machines to investigate the mechanics of the circulatory, respiratory and muscular systems. After 1868 he turned to the study of human and animal locomotion. In the second edition (1885) Marey added a 51-page supplement, Développment de la mêthode graphique par l'emploi de la photographie. Digital facsimile of the 1878 from Google Books at this link; digital facsimile of the 1885 edition from the Internet Archive at this link.

For the second issue the title was changed to La méthode graphique dans les sciences expérimentales et principalement en physiologie et en médecine.

Marey, like Muybridge (No. 650-51), was a pioneer in the use of serial pictures as a method of studying the mechanics of locomotion. English translation, 1895.