BROWN, William Ted
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Recurrent de novo point mutations in lamin A cause Hutchinson-Gilford progeria syndrome.Nature, 423, 293-298, 2003.The authors showed that mutations in lamin A (LMNA) are the cause of Hutchinson-Gilford progeria sundrom (HGPS). At the end of their abstract they stated that "The discovery of the molecular basis of this disease may shed light on the general phenomenon of human aging." Subjects: BIOLOGY › MOLECULAR BIOLOGY › Molecular Biology, GENETICS / HEREDITY › GENETIC DISORDERS › Progeria |