An Interactive Annotated World Bibliography of Printed and Digital Works in the History of Medicine and the Life Sciences from Circa 2000 BCE to 2024 by Fielding H. Garrison (1870-1935), Leslie T. Morton (1907-2004), and Jeremy M. Norman (1945- ) Traditionally Known as “Garrison-Morton”

16076 entries, 14164 authors and 1948 subjects. Updated: January 31, 2025

TOMCHICK, R.

1 entries
  • 1931.6

Enzymatic O-methylation of epinephrine and other catechols.

J. Bio. Chem., 233, 400-401, 1958.
The authors discovered the enzyme "COMT" or cathecol-O-methyltransferase, and determined that it was crucial in the methylation and inactivation of adrenergic and other catecholamine type neurotransmitters.

(Thanks to Juan Weiss for this reference and its interpretation.)

In 1970 Axelrod shared the Nobel Prize in Physiology or Medicine with Bernard Katz and Ulf von Euler "for their discoveries concerning the humoral transmitters in the nerve terminals and the mechanism for their storage, release and inactivation."



Subjects: NOBEL PRIZES › Nobel Prize in Physiology or Medicine , Neurophysiology, PHARMACOLOGY, PHARMACOLOGY › PHARMACEUTICALS › Cardiovascular Medications